Current or recent pregnancy is associated with adverse pathologic features but not impaired survival in early breast cancer
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چکیده
منابع مشابه
Cyclin Dl Amplification Is Not Associated with Reduced Overall Survival in Primary Breast Cancer but May Predict Early Relapse in Patients with Features of Good Prognosis1
Amplification of chromosome 11q13 is frequently observed in human malignancies, including breast cancers. A candidate oncogene at this locus is the CCNDJ gene, which encodes the cell cycle regulatory protein cyclin Dl. Because published data on the relationship between 11q13 amplification and prognosis in breast cancer have been controversial, we investigated the clinical significance of CCNDJ ...
متن کاملObesity is not associated with aggressive pathologic features or biochemical recurrence after radical prostatectomy.
OBJECTIVE To determine whether obesity is associated with adverse pathologic characteristics, positive surgical margins, greater biochemical recurrence rates, and interval to death after primary treatment with radical prostatectomy (RP). MATERIALS AND METHODS A 12-year, retrospective, single-institution analysis of patients treated with RP was performed. Patients were categorized by their bod...
متن کاملCurrent management of pregnancy-associated breast cancer.
Pregnancy-associated breast cancer is the most common malignancy during pregnancy with an expected rise in incidence. The belief in the need for termination of pregnancy and that chemotherapy is contra-indicated during pregnancy is challenged by recent evidence. Patients can consider breast-conserving surgery and sentinel lymph node biopsy with acceptably low fetal risk from radiation exposure....
متن کاملCCL22 16C/A Genetic Variation is not Associated with Breast Carcinoma in Southern Iranian Population
Background: CCL22/MDC is a CC chemokine with a critical role in regulation of the immune balance in physiological condition. CCL22/CCR-4 ligation has been documented to participate in the migration of regulatory T (Treg) cells and Th2 lymphocytes to the site of breast tumors; circumstances that are known to be associated with poor prognosis. Objective: To investigate the association of a single...
متن کاملBreast Cancer Associated with Dermatomyositis
Dermatomyositis (DM) is a rare idiopathic inflammatory myopathy with characteristic skin lesions. Case series have shown an association between dermatomyositis and malignancy. Malignancy has been found in 15-25% of the adult patients with dermatomyositis. A 50-year-old new case of breast cancer, was admitted with muscle weakness and inability to walk. Physical examination revealed fever, perior...
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ژورنال
عنوان ژورنال: Cancer
سال: 2011
ISSN: 0008-543X
DOI: 10.1002/cncr.26654